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Before you use NOLVADEX

When you must not use it

Do not use NOLVADEX if you are pregnant, trying to become pregnant or are breastfeeding. We do not know if it is safe for you to take it while you are pregnant. It may affect your baby if you take it at any time during pregnancy.

Your baby may take in NOLVADEX from breast milk if you are breastfeeding.

Do not use NOLVADEX if you are allergic to tamoxifen or any of the other ingredients in NOLVADEX.

Do not use NOLVADEX for reducing the risk of breast cancer occurrence if:

  • you are taking medicines used to prevent blood clots such as warfarin
  • you have had deep vein thrombosis (DVT – blood clots in veins of your leg) or pulmonary embolus (blood clots in your lungs).

Do not give NOLVADEX to children. There is no experience of its use in children.

Do not take after the use by (expiry) date printed on the pack. It may have no effect at all, or worse, an entirely unexpected effect if you take it after the expiry date.

Do not take NOLVADEX if the packaging is torn or shows signs of tampering.

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Before you start to use it

You must tell your doctor if:

  1. you have any allergies to:
  • tamoxifen, the active ingredient in NOLVADEX
  • any of the other ingredients in NOLVADEX listed at the end of this leaflet
  • other anti-oestrogen medicines
  • any other medicines


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Taking other medicines

Tell your doctor if you are taking any other medicines, including:

  • oral contraceptives (‘the pill’)
  • hormone replacement therapy
  • medicines used to thin your blood e.g. warfarin
  • rifampicin
  • chemotherapy
  • any medicines that you buy at the chemist, supermarket or health food shop.

NOLVADEX should not be taken with aromatase inhibitors such as anastrozole, letrozole or exemestane.

These medicines may affect the way NOLVADEX works or may not work as well. They could also cause side effects if you take them with It.

Your doctor or pharmacist can tell you what to do if you are taking any of these medicines.

If you have not told your doctor about any of these things, tell them before you take any NOLVADEX.

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Follow all directions given to you by your doctor or pharmacist carefully. They may differ from the information contained in this leaflet.

Your doctor or pharmacist will tell you how many tablets you will need to take each day.

If you do not understand the instructions on the box, ask your doctor or pharmacist for help.

How much to take

Your doctor will decide how much NOLVADEX you need to take.

The usual dose is 20 mg of NOLVADEX each day.

This is two 10 mg Nolvadex tablets taken together or one 20 mg Nolvadex-D tablet taken once a day.

Some people need to take 40 mg once a day. Your doctor will tell you if this is necessary.

Swallow your NOLVADEX whole, with a full glass of water. Do not chew or crush the tablets.

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When to take it

Take NOLVADEX at about the same time each day.

It does not matter if you take NOLVADEX before, with or after food.

How long to take it

Continue taking NOLVADEX for as long as your doctor or pharmacist tells you to.

If you forget to take it

Do not double the dose to make up for the dose that you missed.


Immediately telephone your doctor or pharmacist or the Poisons Information Centre (telephone 13 11 26), or go to Accident and Emergency at your nearest hospital immediately if you think that you or anyone else may have taken too much NOLVADEX. Do this even if there are no signs of discomfort or poisoning. If you take too much NOLVADEX you may experience problems with the rhythm of your heart.

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While you are using it

Things you must do

Be sure to keep all your appointments with your doctor so your progress can be checked.

Tell any other doctors, dentists and pharmacists who are treating you that you are taking NOLVADEX

If you are about to be started on any new medicine, tell your doctor, dentist or pharmacist that you are taking NOLVADEX.

If you go into hospital, please let the medical staff know that you are taking NOLVADEX.

Things you must not do

Do not get pregnant while you are taking NOLVADEX.

Ask your doctor about reliable methods of contraception while you are taking NOLVADEX.

Do not take NOLVADEX to treat any other complaints unless your doctor tells you to.

Do not stop taking NOLVADEX, or lower the dosage, unless you have discussed this with your doctor.

Things to be careful of

Be careful driving or operating machinery until you know how NOLVADEX affects you. Some patients may experience dizziness, fatigue or light headedness.

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Additional information


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