Description
Attention Deficit Hyperactivity Disorder
Metadate CD: Initial, 20 mg PO qAM before breakfast; may increase in 10- to 20-mg increments, not to exceed 60 mg/day
Ritalin LA: Initial, 20 mg PO qAM; may adjust dose in weekly 10-mg increments, not to exceed 60 mg/day (patients requiring a lower initial dose may begin with 10 mg). Buy Ritalin 10mg, for sale online in Australia
Concerta: Initial, 18-36 mg PO qDay; may increase by 18-mg increments at weekly intervals; maintenance dose is 18-72 mg/day
Metadate ER, Methylin ER, and Ritalin SR: Duration of action is approximately 8 hr; may use in place of methylphenidate IR tablets when 8-hr dosage of methylphenidate ER and SR tablets corresponds to the titrated 8-hour dosage of methylphenidate IR; not to exceed 60 mg/day
Methylin, Ritalin (immediate-release tablets, chewable tablets, and oral solution): 20-30 mg/day PO divided q8-12hr, 30-45 minutes before meals; may gradually increase dose at weekly intervals; some patients may require 40-60 mg/day; in others, 10-15 mg/day may be adequate
Aptensio XR: 10 mg PO qDay in AM; may increase weekly by 10-mg increments; not to exceed 60 mg/day
QuilliChew ER (chewable extended-release tablets): 20 mg PO qAM initially; may be titrated up or down weekly in increments of 10 mg, 15 mg or 20 mg, not to exceed 60 mg/day. Buy Ritalin 10mg, for sale online in Australia
Jornay PM: Initial, 20 mg PO qDay in the evening; may titrate weekly in increments of 20 mg; not to exceed 100 mg/day; initiate dosing at 8:00 p.m.; adjust timing of administration between 6:30 pm and 9:30 pm to optimize tolerability and efficacy the next morning and throughout the day
Adhansia XR: 25 mg PO qAM initially; may titrate upward in increments of 10-15 mg at intervals of at least 5 days; dosages >85 mg/day associated with increased incidence of certain adverse reactions
Narcolepsy
Methylin, Ritalin (immediate-release tablets, chewable tablets, and oral solution): 20-30 mg/day PO divided q8-12hr, 30-45 minutes before meals; some patients may require 40-60 mg/day; in others, 10-15 mg/day may be adequate
Metadate ER, Methylin ER, and Ritalin SR: Duration of action is approximately 8 hr; may use in place of methylphenidate IR tablets when 8-hr dosage of methylphenidate ER and SR tablets corresponds to the titrated 8-hr dosage of methylphenidate IR. Buy Ritalin 10mg, for sale online in Australia
Dosage Modifications
Dose reduction and discontinuation (Adhansia XR or Jornay PM)
- If paradoxical aggravation of symptoms or other adverse reactions occur, reduce dosage, or, if necessary, discontinue drug
- Periodically discontinue treatment to assess condition
- If improvement is not observed after appropriate dosage adjustment over a one-month period, discontinue treatment
Administration
Oral Administration
QuilliChew ER
- Extended-release chewable tablet
- Take once in morning
- May take with or without food
-
Switching from other methylphenidate products
- If switching from other methylphenidate products, discontinue that treatment, and titrate with QuilliChew ER using the titration schedule (see Pediatric Dosing)
- Do not substitute for other methylphenidate products on an mg-per-mg basis, because of different methylphenidate base compositions and differing pharmacokinetic profiles. Buy Ritalin 10mg, for sale online in Australia
Methylin
- Chewable tablet: Take with at least 8 ounces (a full glass) of water or other fluid; taking without enough liquid may cause choking
- Methylin ER tablet: Swallow whole; do not crush or chew
- Take all formulations 30-45 minutes before meals
Ritalin
- Ritalin, Ritalin SR tablets: Swallow whole, do not crush or chew
- Ritalin LA capsule: Swallow whole, do not crush or chew; may open capsule and sprinkle contents on applesauce and consumed immediately
- Take all formulations 30-45 minutes before meals
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Metadate
- Metadate ER: Swallow whole, do not crush or chew; administer twice daily before breakfast and lunch
- Metadate CD: Swallow whole, do not crush or chew; may open capsule and sprinkle contents on applesauce and consumed immediately; administer once daily in AM
Quillivant XR
- Oral extended-release suspension
- Shake bottle vigorously for at least 10 seconds before measuring dose
- May take with or without food
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Aptensio XR
- May take with or without food
- Advise patients to establish a routine pattern with regard to meals
- Capsules may be swallowed whole or opened and the entire contents sprinkled onto applesauce and consume immediately
Daytrana
- Apply patch on hip 2 hr before desired onset; remove after 9 hr; alternate application site
Cotempla XR-ODT
- Take consistently with or without food
- Use dry hands when opening the blister pack
- Do not remove the tablet from the blister pack until just prior to dosing
- Remove tablet by peeling back foil on blister pack; do not push the tablet through the foil
- Do not store tablet for future use
- Administer immediately after opening by placing the tablet on the patient’s tongue and letting it dissolve; do not chew or crush
- Tablet will disintegrate in saliva so that it can be swallowed; no liquid is needed to take the tablet
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Jornay PM
- Not to be administered in the morning
- Following determination of optimal administration time, advise patients to maintain a consistent dosing time
- Advise patients to take the dose consistently either with or without food
- May take capsule whole, or may be opened and the entire contents sprinkled onto applesauce; if patient is using the sprinkled administration method, the sprinkled applesauce should be consumed immediately and not stored and should be taken in its entirety without chewing; the dose of a single capsule should not be divided and should be taken at the same time
- Periodically reevaluate longterm use and adjust dosage as needed. Buy Ritalin 10mg, for sale online in Australia
-
Missed dose
- Take dose as soon as patient remembers that same evening; if patient remembers the missed dose the following morning, skip the missed dose and wait until next scheduled evening administration
-
Switching from other methylphenidate products
- If switching from other methylphenidate products, discontinue that treatment, and titrate with Jornay PM using the titration schedule described above
- Do not substitute for other methylphenidate products on an mg-per-mg basis, because of different methylphenidate base compositions and differing pharmacokinetic profiles
Adhansia XR
- Swallow whole or open capsule and sprinkle entire contents onto 1 tablespoon of applesauce or yogurt; consume entire mixture immediately or within 10 min
- Take the entire contents of capsule sprinkled on the chosen food in its entirety, without chewing
- Discard mixture if not consumed within 10 min; do not store
- Do not divide capsules nor take <1 capsule/day. Buy Ritalin 10mg, for sale online in Australia
-
Missed dose
- Do not administer later in the day
- Do not administer additional medication to make up for missed
-
Switching from other methylphenidate products
- Switching from other methylphenidate products: Discontinue current treatment and titrate with Adhansia XR using titration schedule
- Do not substitute for other methylphenidate products on a milligram-per-milligram basis because of different methylphenidate base compositions and differing pharmacokinetic profiles. Buy Ritalin 10mg, for sale online in Australia
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